Holby City will come to an end after 23 years and a host of famous guest stars.
Here is a look at some of the faces who have turned up in Holby City Hospital over the years.
The TV star joined the cast in series 15 to play a cancer patient called Tim Connor.
He appeared in three episodes in 2013.
The comedian also appeared in series 15, playing patient Darren Harrison.
The Hear’say singer and Coronation Street star popped up in series eight, playing Myrna Morrison in 2006.
The veteran actress appeared in series 14 as patient Bonnie Walters
Before shooting to fame in Killing Eve, Comer had one of her first TV roles in series 12 of Holby City, playing patient Ellie Jenkins.
The Oscar-winner appeared in 2002 as Kim Prebble.
The Black Panther actress appeared in two episodes in series 13 in 2011, playing Ellie Maynard.
The former Coronation Street star made a guest appearance as new nurse Kirsty Brompton in 2014, her first part in a TV drama since she left her role as Rosie Webster on the ITV soap in 2012.