West Ham have granted Ukrainian winger Andriy Yarmolenko compassionate leave so he will miss the visit of Wolves.
Vladimir Coufal is out after groin surgery and fellow right-back Ryan Fredericks has a groin strain, so Ben Johnson will come in.
Manuel Lanzini is back in training after an Achilles problem but Arthur Masuaku and Angelo Ogbonna are still recovering from a knee injuries.
Nelson Semedo is likely to miss out for Wolves after hobbling off in the 2-1 loss at Arsenal on Thursday.
The full-back appeared to be struggling with his hamstring and was replaced by Jonny for his first appearance in 10 months following a serious knee injury.
Pedro Neto will be pushing for his first start having returned from a similar spell on the sidelines, while Willy Boly and Yerson Mosquera are fit.
West Ham provisional squad: Fabianski, Areola, Randolph, Johnson, Dawson, Zouma, Cresswell, Diop, Baptiste, Alese, Rice, Soucek, Fornals, Noble, Kral, Chesters, Lanzini, Benrahma, Bowen, Vlasic, Antonio, Okoflex.
Wolves provisional squad: Sa, Ruddy, Ait-Nouri, Coady, Semedo, Kilman, Boly, Marcal, Jonny, Mosquera, Gomes, Saiss, Neves, Moutinho, Dendoncker, Cundle, Podence, Neto, Trincao, Jimenez, Silva, Hwang.