Aberdeen and Ross County have been given the go ahead to allow 300 fans into their respective stadiums on Saturday.
The Dons’ home match against Kilmarnock and Ross County’s match against Celtic at Victoria Park will be played in front of a limited audience following discussions between the Scottish Government and the football authorities.
However, the proposed pilot events involving Rangers and St Mirren will not go ahead following the extension of coronavirus restrictions in the west of Scotland.
Sports Minister Joe FitzPatrick said: “No final decision has yet been taken regarding the general resumption of stadia events with restricted numbers of spectators and nothing should be taken for granted at this stage.
“However, the Scottish Government has agreed that the Scottish Professional Football League (SPFL) can hold two pilot events, each with 300 home supporters only, on September 12.
“A lot of work has gone on behind the scenes in recent months to create the protocols and testing regimes to allow top-level professional sport in Scotland to resume, and this arrangement follows extensive discussions with the Scottish FA, SPFL and clubs about public safety – particularly in relation to physical distancing and hygiene measures.
“The football authorities and the clubs involved have also been able to review and learn from the pilot event staged by Scottish Rugby on August 28 and we are confident there will be strict protocols in place at these two initial pilot football events.
“We are keeping all pilot events under close review.”
Each of the home clubs will also provide a post-match report on operational delivery to inform guidance for future pilots.
No date has been confirmed for the general resumption of stadia events outlined in the Scottish Government Route Map out of the Covid-19 crisis.
SPFL chief executive Neil Doncaster said: “The Joint Response Group (JRG) is pleased to have received confirmation of pilot events at two Scottish Premiership fixtures on September 12 and I would like to thank the respective home clubs – and indeed all 12 Premiership clubs – for the comprehensive Return to Supporting plans.
“We look forward to building on the successful supporter rugby pilot at BT Murrayfield and I know that clubs take the responsibility for the safe return of supporters seriously.
“This is another significant step forward for Scottish football and I reiterate the importance of fans to our national game.
“The JRG will continue to liaise with all clubs, especially the home clubs, in the coming week to ensure all protocols and guidance are adhered to and that fans can look forward to a phased return to supporting their respective teams.”