The demolition of a bridge in Stonehaven will begin next week as part of the AWPR construction project.
The structure, which carries the A90 southbound over the B979 at Netherley Road, will be cut into two sections between April 3 and 7.
And, after that work has been carried out, the southbound carriageway will be demolished using specialist equipment.
Transport Scotland has announced the B979 between New Mains of Ury and Glenury Road will be closed from 8pm until 6am every night for safety reasons.
Diversions will be signposted in a bid to keep any disruption to a minimum.
A Transport Scotland spokesman said: “These essential demolition works at Stonehaven have been planned to take place when roads are quieter to minimise inconvenience to road users.
“The traffic management measures in place will enable part of the bridge carrying the A90 over the B979 to be demolished and then reconstructed safely.”
Transport Scotland added the works at Stonehaven will also involve widening the B979 Netherley Road, the construction of new slip roads and the creation of a new roundabout.
Stonehaven and Lower Deeside SNP councillor, Graeme Clark, acknowledged the work will be an “inconvenience” for residents and drivers.
Mr Clark added: “All drivers will have to be patient and understand that a major infrastructure is being built in Aberdeenshire.”
However, Mr Clark believes it will be of “great benefit to all road users” when the project is completed.
Transport Scotland has said the AWPR project will bring £6 billion to the north-east economy over the next three decades.
It also expects to create around 14,000 jobs.